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Show o I aste Loss .2, Jie electron microscope, pinpoints two distinct phases ict of tasting. Henkin calls these two stages "preneural" and "neural." The toreneural has to do with the taste bud itself and with the flow of the tasted substance (he has coined the term "tastant") through he pore at its center to the taste nerve endings right inside. There he neural stage begins, with swift interpretation of just what aste has been introduced, and the instantaneous relay of that information to the brain. How the nerve endings read the "code" of each tastant, and iow the brain translates that code, are mysteries which are not et known to the researchers. Formerly, the taste buds were thought to be actual fend organs." Now Henkin and company have demonstrated hat the taste bud is actually what they call a "chemical sieve." y its chemically controlled opening and closing, it keeps much f the tastant away from the nerve ends inside omewhat the way the eye's iris keeps light away from the ptina or a camera's diaphragm regulates the amount of light Jailing on the mm. j The clue to the chemical control came from research Doctor Henkin was asked to do into why patients suffering from diseases like scleroderma, rheumatoid arthritis, and cystinu:ia suf- erea taste loss alter taking medications containing thiols. A hiol is a sulphur compound that normally occurs in the body nd causes proteins to uncoil and change their shape. Doctor Henkin noted that victims of Wilson's disease, which ends to maintain an excess of copper in the body, suffered no aste loss even though treated with the same rugs. He reasoned, therefore, that too much thiol was throwing he thiol-metbalance out of kilter in the patients who did lose their ability to taste. He proved his theory by giving these parents modest doses of copper sulfate and seeing them regain Jtheir taste in less than a week. taste-sensi- ng thiol-containi- ng al I metals have the opposite effect on proteins causing Ihem to open up Doctor Henkin theorizes that there must be ja "gatekeeper protein" inside each taste bud which responds jOince properly by opening to admit just enough tastant for analysis when thiols and metals are in dynamic balance, but shuts the bud medicines overwhelm the metals. up tight when The result: taste loss. The remedy: powdered metals to restore the balance, and the taste. Doctor Henkin has yet to prove there is such a "gatekeeper rotein," but from the results of his and his colleagues' work, he odds seem to be that they will. Among the known benefi ciaries of that work are cancer patients whose loss of taste from the excess thiols produced by the malignancy can - - ! . iLA r amaiiaU rsvA ri1fnA aipiKf WVCIVOIUC waauy suuait Oy Having IHCIII UUUK cuuugii restore balance. the normal jto J The research by Doctor Henkin and his colleagues has caused .the old "tongue maps" to be thrown out the These maps supposedly localized those places on the pngue's surface which are sensitive to the tastes of salt, sweet, jbitter, and sour. By testing taste sensations in different areas of jthe tongue and palate, the researchers were able to show that the alate and pharynx have important and specialized taste func- ions along with the tongue. The ability to detect sour and bitter tastes, for example, was ound to be concentrated largely on the palate. As a result of his discovery, plate makers are now designing upper dentures o admit food and drink to the newly identified jareas of the palate that used to be covered by the old dentures. The denture wearers who will be savoring good food again epresent only a portion of the large numbers of elderly and ot so elderly people who, thanks to the work of the Henkin esearch team, will no longer have to bemoan the fact that "the pste has gone out of living." $ thiol-containi- ng bone-marro- w -.. metal-to-thi- 19th-centu- JX 1- ol win-jdo- ry taste-sensiti- A of the w. ve ; 1 c9 K " to to How can you get rich some day? Make a killing on the stock market or invent a gadget like the hula hoop? For most of us, these are just dreams. . . . month after month? That's concrete proof! You know those &ds wouldn t be repeated over and over again unless they were bringing in big cash profits to their owners. that there is a way to get rich possibly only one sure way? Most fortunes, as you know,, are made by people who own The Secret ...... a hit record But have you ever stopped to think their own business. Perhaps you've thought of starting a small business of your own . franchised drive-in- , or maybe a service business. Trouble is, you need $10,000 to $15,000 to get started and even then it's a gamble with slim chance jt ever making really big money. But there is one business which could make you rich almost overnight! And the beauty of it is, you can start on a shoestring during your spare time, even while holding your regular job. .a Cash by The business is Mail Order and it's fabulous! Come up with a 'hot' new item and WHAM! It strikes like a bolt of lightning! Suddenly, you are deluged with cash orders from all over the country . . . MORE MONEY than you could ever make in a lifetime! Like the Vermont dealer who ran one ad in Sports Afield Magazine. His ad pulled 22,000 orders ever A HALF MILLION DOLLARS IN CASH! There is no other business where you can make a forture so quickly! A beginner from Newark, N.J. ran his first small ad in House Beautiful offering an auto clothes rack. Business Week reported that his ad brought in $5,000 in orders. By the end of his first year in Mail Ordr, he had grossed ... over $100,000! Another beginner a lawyer from the midwest. Bold an idea by mail to fisherman. Specialty Salesman Magazine reveals, "he made $70,000 the first three months!" It's a fascinating business! Running ads in newspapers and magazines . . . mailing gift catalogs . . . getting cash orders in your daily mailsteady as clockwork. There is no other business where you can start on a shoestring and pyramid your profits without investing in merchandise! One husband and wife mail order team took in $40,000 selling one item. They obtained FREE ads in na- tional magazines . . . didn't invest a cent in merchandise, and even got the supplier to ship all orders for them! These exceptional cases are absolute proof that you can get rich in your own Mail Order business. Very rich. Even a U.S. Gov. Report stated: "A number n Mail Order enterprises of make up to $50,000!" Pick up any magazine. Notice how the same mail order ads are repeated ica! And now, with more people moving to the suburbs . . . the population explosion . . . and the expanding teenage market . . . e are on the verge of the BIGGEST BOOM in Mail Order history! Now, with the help and backing of Mail Order Associates, Inc., of Mont-valN.J., you can follow the same proven steps to Mail Order success-us- ing the 'secret' of financial leverage! e, The secret of getting rich in Mail Order lies in financial leverage. It's a little-know- n, almost secret method using other people's capital to make money for you! You can get thousands of dollars worth of advertising in big national magazines without investing your own money! And you don't have to write a single ad. Tested and proven ads are prepared for you by experts. Reinvest the profits from your first successful ad to get more, larger ads, and the profits begin to snowball! It's like building a chain of stores . . . each new store puts more money in your pocket. You mail out beautiful catalogs which offer hundreds of dollars worth of fine, quality gifts yet you don't invest one Start Now We supply you with beautiful gift catalogs throughout the year. All products are dropshipped for you, with up to mark-up- ! 100 You get free samples of mail order items, plus monthly trade reports on 'hot new products . . . tested, successful ads are sent to you monthly. You get advertising directories, postal laws, complete courses, expert guidance EVERYTHING you need to practically guarantee YOUR SUCCESS. Why? Because our business depends upon your success. It's mutually profitable! A recent feature article in Income Opportunities Magazine stated, "Mail Order Associates Inc., offers the most Mail Order program comprehensive ever offered to beginners." They go on to say, "This could be the opportunity you've been looking for. A chance to n get in on the ground floor in a business which we believe is on the verge of a new boom." top-selli- little-know- Lr- - -- r ' - I j Free We are now a limited number of charter members in our new Mail Order Program. No previous experience is required but you must be over 21. If you ait sincerely interested in starting a profitable business of your own if you can see the tremendous advantages which Mail Order offers . . . then ACT NOW! Mail the coupon today, or simply send your name and address on a postcard. No salesman will call. We will send you a free book gift catalog, reprints of feature articles, plus complete facts about our program. Wri to: thrill of reeeMno money in you mall It ono yow'lf never tiro of Tfco cent of your own money in merchandise! Your catalogs are printed with your name and address, so all orders come to you. Everything is for you, and there's up to mark-up- ! 100 You pocket the cash profits immediately even before the orde. i are shipped to your customers! Repeat orders alone, just from mailing catalogs, could bring you a steady income for the rest of your life! Yes, Mail Order is the most profitable business in Amer- "drop-shippe- Proof ott lit m (2) fastest-growin- ranf ... d" Moll Order Anockiltt, Inc., Dept. 295 Monfvole, Now Jeney 07645 g, era XSC39 plet reprint! ef Moll Oreer ortkU Mail Order Associates, Inc., Dept. 295 Montvale, New Jersey 07645 "lea$e roth complete detail on year Mail Order Program. wnderttand every Hung free and there it abeoWtely no obligation. I am over 21. I Name , one-ma- i it Family Weekly, November 22, 1970 31 City .State. Hp |