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Show eee HISMANAL” cane sonenteoricrr oneer oe oes oss Belore ter macrolide antics. ncuing trleardomycin, ait. ys, Selecormended, diese coms compete prescriby ror: ‘HISHABAL bets are indicated for he rebe! of symtoms al ae ie cee, * gsi cantinaalma eat Mth we tet mia WESHAINL shout nt be used a5 29 fn product ‘to sicrease the dase im an att to accelerate Be onset Chea tus have act ben conduc to eve the etecoenessofHSMAVALihcomo TRATION OF ASTENAZOLE WT RESULTING INELEVATED PLASMA LEVELS OF ASTEMIZOCE Al1D DESMETHYTA SUGGESTTHAT CARDIOVASCULAR ELEVATIONOFASTEIGORE TABLELEVELS. RESULT CONCOMITANT ADMRSTRATION OF ASTEMIZOLE TH ITRACONAZOLE IS ALSO COMTRAIWDICATED BASED THe OF ITRACONAZOLE AND KETOCONAZOLE. I VITRO-DATA SUGGEST THAT q ALESSPRORDUNCEDEFFECTOWTHE BIOTRANSFORMATION SYSTEM RESPONSIBLE FOR ‘THE METABOLISM OF ASTEMIZOLE COMPARED TO NETOOONNZDLE (SeeRSISard PRECAUTIONS Draco) ISUAJAL coca in parts th cu ype Senotatylosemeoanoheracegees, en 4 he poet beet ses Be pot kW es. oTPROLIANTATTN mgeen hebody fo25 ag364 ments ‘ehno osng cueson bas6bese lerae ili i PRECEDED OY EPGOOES a eranCreSesedto) gs "DacaDas ChanlOctO Prenzweseeel)irene With HISMANAL, you get relief of your runny nose, sneezing, and itchyAwatery eyes...without getting drowsy. In fact, HISMANALcauses no more drowsiness than a sugar pill.* What's more, eon you only have to take HISMANAL once a day for a full 24 hours’ worth ofrelief HISMANALis available by prescription only. So ask your doctor today about HISMANAL. And wake up to a different kind of allergyrelief. WARNING: HISMANAL should be taken only as directed, onetablet a day, Do not increase the dose in an attempt to speed the action of HISMANAL It may take a few days of regularuseto feel the action of HISMANAL "The reported incidence of drowsiness with HISMANAL (7.1%) in clinical studies involving more than 1600 patients did not differ significantly from that reported in patients receiving placebo (6.4%), Caen shed 0b wed when Weng gers wth ed ‘game ica SeCORTRARNICATIONS and VARHINGS sects tr assent farmegatgpoegts FOR A FREE HELPFUL BOOKLET CALL 1-800-392-2602 © Janssen Pharmaceutica Inc. 1995 a roe canna. (Set at (GS BOL) Concomtnt reomsean of ase wth HISMANAL must not be taken with the prescription antifungal medicines itraconazole (Sporanox®) or ketoconazole (Nizoral?)tablets, or the prescription antibiotics erythromycin or clarithromycin. People with serious liver disease should not take HISMANAL HISMANALhas been associated with rare occurrences of abnormal heartbeats and heart attacks. In very rare cases, this could be fatal. Tell your doctorbefore taking HISMANAL if you have anyliveror heart problems. It's also importantto tell your doctorif you ever become faint, dizzy, or have irregular heartbeats while you are taking HISMANAL, Ask your dactor today about PRESCRIPTION-ONLY HISMANAL (ASMIZOIE The seasonal allergy relief you wait...without the drawsiness* SPLHS-241 Please see adjacent important precautionary information. |
