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Show Page 2S THE HERALD, Ptovo. Utah, Sunday. August 22, Cloner 1982 Add up the S avinqs Sees Many Problems 25 JOLLA, Calif. One of the who researchers LA (UPI) - achieved the first known cloning of a human gene affecting behavior and intelligence says there are a lot of problems to overcome before defective genes can be repai- Super Cords for boys and girls. All It's a super sale! Tough wearing Super Cord" jeans at prices you'll love. Of durable polycotton midwale corduroy that's neat for class and rugged for play. Sale ends August 28th. red. "We can't jump into it and say gene therapy is here. We have many problems to resolve before that," Dr. : Percentage is Theodore Friedmann, pediatrics professor at the University of California's San Diego School of Medicine, said Tuesday. Friedmann and three associates successfully isolated and reproduced a off regular retail. 25) off Selected fleece activewear for kids. gene which, when defective, causes a form of severe mental retardation that causes its vi- ctims to mutilate themselves. Called syndrome, the disease is Lesh-Nyha- off Sale 6.75 to 12.75. Reg. $9 to $17. Activewear in acrylic, acryliccotton and poly cotton blends. Select hooded sweatshirts with pouch pockets, jogging suits with jackets and elasticized waist pants. Sizes for boys and girls. Great fashion colors. n zip-fro- nt characterized by compulsive biting, and if not restrained, its victims will gnaw off their own lips and fingers and bite at anybody who comes Big girls' hooded sweatshirt Big girls' jogging pant....; Little girls' character jogging suit near. Announcement of the cloning in Tuesday's edition of Proceedings of the National Academy of Sciences triggered some speculation a treatment might be near for such devastating symptoms as n syndrome. Big Big boys' jogging suit boys' corded jogging suit Other styles savings. of Reg. $11 $9 Sale 8.25 $16 12.00 $16 $17 12.00 12.75 fleece activewear also on sale at similar Lesh-Nyha- "We have Eroblems many to resolve Friedmann said. But, he said, being able to identify and study specific genes related to diseases increases the possibility of preventing or treating them. With the ability to clone the genes, scientists will have them in sufficient quantity for study. The gene is thought to be the first ever isolated that has an effect on in telligence and behavior It programs the body to produce the HPRT en zyme, the absence of which results in Lesh Nyhan Syndrome that oc curs in one of every 100.000 births. The ultimate goal of the research is to determine how to trigger the miss ing enzyme in the body, or to find a way to replace it before its absence results in perma nent damage, Friedmann said, then added, exten sive research is still re quired. "Next is to study how the gene functions in new cells, its structure in chromosomes, and what's wrong with it," Friedmann told UPI. Friedmann said before extensive work in humans can begin, "We need model genes and model diseases that can provide the groundwork and help us determine how genes can be transferred, manipulated and controlled. The linked disorder is passed by female carriers to half of their male children. The ' retardation is characterized by aegres sion and The disease can be detected bv prenatal testing, covered can go several the first 25 but if not dis before birth, it undetected for months before symptoms show up. 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