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Show Puge JO-T- HL1ALD, Provo, Uuh, Thursday, October HE 12. 1978 Pioiein Anti-Vir- al Campaign '78 the Substance Known As Interferon a Cancer Fighter? Is Oklahoma Boren has By Dianiu Sinovlc NEW YORK (NEA) Why is the American Cancer Society (ACS) now preparing to spend S2 million for clinical tests of interferon, a bodily substance known to the chemical world for 20 years? Democratic - yf ; JfhI !T v vv:-a . ' to human Boren is patients. ililitfpill' T in p J a strong favorite to win in V November, 1 children and young adults v.V. have survived the bone cancer osteogenic sarJ . . -- 'iii . i i. coma after being treated CHARLCIE RICHARDSON, a patient receiving treatwith high doses of inment for cancer at The University of Texas M.D. terferon. Anderson Hospital and Tumor Instate, gets a shot of According to the ACS, interferon from Melinda Echeverria, an Immunoththe survival rate of these erapy research nurse. patients was 70 percent over a period of three years, compared to norFriedman. "It is secreted preventing the body from itial symptoms. The mal expectations of percent in patients by the host cell almost producing more an- molecule is also extremetreated by surgery alone. like a hormone, and while tibodies than it needs. ly active. Little of it is reInterferon produced by quired to activate the But interferon has its highest concentration several catches. is local, it can travel to most of the body's cells in defense system. And in"So far, the experimen- remote areas and render response to a virus is the terferon, because it is tal use of interferon as an its protection there." fibroblast type. produced naturally within ' An attacking virus unLeukocyte interferon, the body, is apparently agent for specific kinds of cancer is leashes its genetic infor- the type used in the ACS harmless to the cells of more or less a shot in the mation into the cell. This test, is produced only by' the body. dark," says Dr. Robert information competes leukocytes, while blood Why does interferon apFriedman, chief of the with the cell's own infor- cells of the immune pear significant in cancer treatment? experimental pathology mation for control. The system. lab at the National In- viral RNA duplicates "In addition to inExactly how interferon stitutes of Health, in the itself and spreads to sur- works in the body is yet to terferon's anti-virjournal CA. rounding cells. The in- be understood. properties, we now think The molecule is short- terferon triggers a secon"On the molecular it is That is, lived within the body and dary site that prevents level, we still don't know interferon has a selective protection declines rapid- the virus from copying its how it works," says Dr. ability to prevent ly within the cells. It is genetic information in Frank Rauscher, ACS cancer," Dr. Rauscher senior vice president for says. also species specific. the surrounding cells. The body, once at- research. "But you don't That is, interferon As a cancer treatment, produced by a chicken tacked by the virus, have to know how a drug manufactures antibodies works to use it in treat- interferon would be inthe chicken; Protects interferon that are programed to at- ment as long as it is jected into the tumor sites to supplement the protects the human. tack the particular in- safe and effective." Animal and human in- vader. These antibodies Interftron's advan- body's natural supply of terferon cannot be appear several days after tages as a drug are the substance. the interferon. If the in- numerous. Interferon switched. In addition to the ' This leads to the most vader should reappear, reacts to a broad range of promising results of the crucial drawback in in- the antibodies recognize viruses. Instead of Swedish tests, 15 breast terferon testing, and the it and destroy it. Specific responding to a specific cancer patients have reason for the lag antibodies are formed for virus, as does the an- been treated with inin its use:' the limited specific viruses. tibody, the interferon terferon at the M.D. Interferon also helps moves against any viral Anderson Hospital and availability of human interferon. The price, as a regulate the immune invader, and a number of Tumor Institute in result, is extremely high. system of the body, viruses have similar in Houston. The ACS estimates a cost of per patient for the clinical tests. j. Finland supplies most of the world's clinical interferon. The Finnish Red Cross collects and processes blood through massive drives. But large quantities of whole blood anti-canc- Senate runoff primary by 100,000 votes over former Rep. Ed Edmondson, who accused Boren of being a "closet Republican." Both Boren and his Republican foe, former Oklahoma State University President Robert Kamm, label themselves as conservative. relative unknown in cancer treatment, ina protein terferon A Clinical testing on humans has centered primarily in Sweden, where 34 patients If Gov. David a problem in his race to recapture a Senate seat for Oklahoma Democrats, it may be that he sounds too much like a Republican. The problem, if it exists, did not keep Boren from winning the recent -- produced by cells to ward off invading viruses has been shown to reduce the size of tumors in experiments with animals as well as in scattered CITY OKLAHOMA (I'PIi er al anti-mitoti- c. ar although Kamm, an admitted underdog, contends he is gaining. Democrats likewise are favored to retain the governor's office and their current 1 ratio in Congress. Both Senate candidates have endorsed the 5-- Fighting for the Right recent primary battle. A labor spokesman says labor may sit out the general election. "There's not much enthusiasm," he said. "Some feel it's better to have six years of Kamm than 30 years of Boren." Neither candidate has endeared himself Kemp-Rot- The winner will Sen. suc- Dewey m being a homosexual, prompting him to swear on a Bible at a televised news conference that he is not and has never been a homosexual or Pharmacy est Center-Prov- o Phone Bartlett, whose election six accused by a minor candidate in the primary of elsewhere, including the 2nd district, where newcomer Mike Synar oustd chairman Paula L'nruh is incumbent Ted Risen-hoovin the primary. making a strong bid to unseat Democrat James R. Boren, a Rhodes Jones, who is seeking his scholar and son of former fourth consecutive term. Rep. Boren, served eight years in the legislature Democrats appear to before winning the goverto be comfortably ahead norship in 1974. He was former state Republican district, labor, with attacks on OSHA and the 1973 "labor reform" bill, coupled with endorsement of ceed In the 1st congressional 373-728- 8 years ago gave Oklahoma two Republican senators for only the second time since statehood in 1907. Bartlett, a former governor, is suffering from lung cancer and is retiri- SJohnson ng. Johnson DISPOSABLE DIAPER-S- Karnrn's hope of overtaking Boren apparently lies in what may be a better party vote organiza- tion, improvement in name recognition and how well Kamm can atinKemp-Rot- h tack Boren's record as come tax bill. Both have governor. attacked President In the governor race, Carter's energy policies, Democrat George Nigh, the federal government, who has spent 16 of the federal judges, "irr- past 20 years as lieuteesponsible federal spen- nant governor, is favored ding," and "the federal to beat Republican Ron bureaucracy." Shotts, a former d Both support a Oklahoma University cut in federal in- football star. Shotts has called for come taxes, a balanced federal budget, in- cuts in the state income creased defense funding, tax and freezing the state payroll. Nigh also has building of the Bbomber, deregulation of promised tax cuts but oil and gas prices and in- also has proposed increased federal funding creased state spending for Oklahoma water pro- for highways and education, to . financed from , jects. Kamm, 59, who en "increased tourism and dorsed the Kemp-Rot- h industrial growth." bill seven weeks ahead of Boren, has accused the governor of & GOP-sponsor- 25 Overnighters box 198 ToddlerS Umited Quantities box one-thir- Myadec Vitamins in tablets 30 freest -l R95 O Theragren Vitamins ISO Ttbltts 60 FREE stealing Republican programs. While Democrats outnumber Republicans 1 in Oklahoma, polls indicate Boren is doing well not only in the normally Democratic regions but the traditonal GOP areas in the rural west and north. Boren was not sup ported by either teacher organizations or labor, two groups that normally back Democrats, in his 3-- h Cuddly 30,000-tOrt3S,0- Toy IPlFAILTr2(BEAIFIF yield only minute in- amounts of processed terferon. A possible alternative .source involves the oo JEoat GOURMET DISHES P .; You will love these cuddly toys that are machine washable. Everyone loves stuffed animals and these wonderful toys will be cherished for years to come. gene-splici- technique developed at the City of Hope National Medical Center in Los Angeles. Researchers there produced the brain hor-imo- somatostatin in ; 1977 and insulin earlier this year. A similar breakthrough ;in synthetic interferon could eventually supply research and medical ; facilities with plentiful 'amounts of the molecule at a much lower price. i However, City of Hope ; experts say that until in; terferon's anti-canc- Pocket Pets w m (I Reg. $1.39 S7E U c) Friendly Faces V(2) Reg. $1.39 n 95 Mini Pets (p)(o)( n 95 Lh Lil' Loves Reg. $2.50 er .'qualities are, indeed, proved, little work on ' synthesizing such a com- plex molecule could be justified. . .virus replication by a number of different mechanisms," says Dr. 'Snake Stomp' In Oklahoma 5 Piece, 1 Place Setting 9 Okla. ." 00 A" M'1 orornDted the snake CT$ ''If novelty gifts. H- mm Wittman's attorney, I Tom Stringer Jr., called ; the event "an obvious satire on this silly dance ordinance. "It's not a dance, it s a snake stomp," Stringer said. dance The ordinance received public 2C support during an Aug. also which referendum, outlawed possession of That poisonous snakes. cL Reg. $4.95 Only At ft oqq Perky Puppets We have gifts for everyone. Come in and see our large selection of beautiful pottery, cards for all occasions and NOW .popular in Henryetta, s) Reg. $6.95 Sug. Retail Price $995 HENRYETTA, Okla. Neither dancing (UPI) nor poisonous snakes are But the town's anti dancing, anti poisonous - snake ordinance has inspired Jim Wittman to the first Greater organize j Henryetta Snake Stomp - for Oct. 14 and the affair 1 is B.Y.O.S., which stands - for bring your own snake. l Floppies "Interferon inhibits - in - r OFF I WHERE SHOPPING IS AN ADVENTURE 0 32 W. Center, Provo, Sale Ends Thursday, October 19, 1978 375-930- ! TCfcjp Gin ilsfl n 5Hrt Hvn 'tint |
