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Show -- rayr,r "fT'TTT fTTrrr V SulMamt )lav Ilormom-IJK- ( LJ. VT-- H l '' r -- m vV; IJr"T"v"" tem attack the victim s own body has prompted researchers to look fur a way to target only the wayward cells Science's ability to produce monoclonal antibodies, which will attack only specific cells, has led rheumatologists to use antibody therapy in mice with a rheumatic disease. Unfortunately, says Dr. Cannon, it s not yet possible to produce antibodies that will recognize and destroy only the abnormal white blood cells. The problem is that immunity is not a bad thing, Dr. Cannon says. It s important that you don't wipe out the whole system." While research on new therapies Tribune Medical W riter human hurmone-hksubstance, initially considered a potential treatment lor canter, may be effective against rheumatoid arthritis. University of Utah researchers hope to participate next year in a study of gamma interferon to determine whether the substance does indeed alleviate symptoms of joint disease ''The theory is. in lab experiments gamma interferon has been suggested to increase immune activity," says Dr Grant Cannon, a rheumatologist at the U. of U. Health Sciences Center 'When interferon was given to patients with cancer and arthritis, they reported an improvement in arthritis symptoms. According to Dr. Cannon, "that finding was surprising. Although the cause of rheumatoid arthritis is unknown, victims of the disease have immune system abnormalities. But it's uncertain whether the arthritis is a cause or result of the immune system malfunction. V'We don't know whether it's a chicken or an egg, basically, says Dr. A e mt Drugs that suppress the immune response are used to treat the pain, stiffness and swelling that characterize the disease. The finding that interferon, which appears to stimulate the immune system, made arthritis Victims feel better "didnt make sense, Dr. Cannon says. . He hopes the U. of U. will be one of a small number of medical centers to further test the effectiveness of interferon on arthritis patients. Until recently, it wasn't possible to produce chough of the substance to study it on a large scale. But Biogen, a company that uses genetic engineering techniques to produce the substance, plans to launch a national study of interferon this January., Dr. Cannon said the proposed study will involve comparing patients who receive standard therapy for arthritis with those who receive interferon in addition to their regular therapy. If the research is approved by the U. of U'.'s Institutional Review Board, Dr. Cannon will be the universitys principal investigator on the study. Results of the only clinical study done to date on interferon were discussed recently at a national symposium on therapy of rheumatic diseases. The conference, sponsored by the Utah Arthritis Foundation and ry r W V!s -- Clearance Sale Sport Coats 100o Wool Tweed or Cotton Corduroy tribune In the meantime, research on less exotic therapies is aimed at reducing the pain and misery of arthritis. The U. ot U. rheumatology department, for example, is comparing the'effec-tivenes- s of injectable gold salts a with sulfasalastandard therapy zine, a drug used in this country to GREATEST SELECTION IN OUR 80 YEAR HISTORY Thursday Morning, December Utal)XMenAills CLOTHING FOR MfcN Section Page C 1 1910" VALUES FOR YOUR HOME SINCE WE'RE CLIMAXING OUR 75TH DIAMOND JUBILEE WITH OUR BIGGEST EVER . . . r 4 GIFT WITH EVERY PURCHASE DURING THIS Number Of Clearance Items We've Had In Years, And We're Marking Them Down To Move Them Out During These Final Few Days Of 985. 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No Special to The Tribune OGDEN Richard Sadler, a professor of history at Weber State College, has been named dean of the college's School of Social Sciences. His appointment, which takes effect July 1 next year, was approved during a recent meeting of Weber States Institutional Council. , "Dr. Sadler was appointed to that position on a temporary basis last July while the college searched for a permanent dean. U'Dr. Sadler has the confidence of the faculty and has done an excellent job as the acting dean. We would like to see him continue in that position," said Robert B. Smith, vice president fqr academic affairs. vTlie history professor has been at the college since 1969, where he has served five years as chairman of the faculty Senate. He received a Presi-dential Citation in 1979 for his work as chairman of that organization. In 1981, he received the Presided-- I tial Distinguished Professor award and in 1972 was chosen Professor of the Year by the Weber State Associated Students. He has been a member of the Dean's Council, the College Planning Council and the School of Social Sciences Ranking Committee. He is a member of the Western History Association, the Organization of American Historians, the Utah Historical Society and the Mormon History As-sooiation. He serves as editor of the I Join rial of Mormon History, Dr Sadler earned his graduate degrees from the University of Utah adapters css, needed. Choose either ColotTrak set with cable direct recess remote and n channel time & numbers. PORTABLE, VERSATILE, AND VHS COMPATIBLE NFW RCA'S RECORDER AND UNIT, PRO WONDfR IN CAMERA & UNLIKE THAT NEFD SPECIAL A SELF OlHfR TAPES. IS VHS VIDEO CONIAINED CAMCORDERS PRO WONDER VHS CASSETTES NO FUSS NO ADAPTfRS. AND NO CONFUSION STIREOrf USES STANDARD WITH TVIMO DC - uses VHS COMPATABIIITY standard VHS cassettes loi playback an your Isome VLR no in between steps FULL Mtt'Y Playback K LCD c. liqhlwf igh! 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Included Control Powr Zoom Lam btlry CASE lip V.rj, ConUnt Whtla Only Ocfciqn t i lb wdh deluxe WITH PURCHASE S ' EVERYTHING OUR MOST POPULAR, SUPERB VALUE 25" diagonal ' t WOMEN FREE jWeber Names Social Sciences Dean 4 & 59 West South Temple treat colitis. . -- $90 26, 1985 immuno-rriodulutors- I Reg. to 165.00 ANNIVERSARY tracted national and international experts to the Westin Hotel Utah. iBiogen physician Dr. John Schindler said the interferon study, involving 33 patients at a Wichita, Kan., medical center, showed the agent is safe enough to undergo a major clinical study. 'While interferon is probably the " most promising of the new being studied as treatment for rheumatic diseases, it isn't the only one. Cyclosporine, an immune system repressor that has dramatically improved the survival rate oj organ transplant patients, seems tO work" on rheumatoid arthritis. (But its toxicity, says Dr. Cannon, is a problem. Since cyclosporine has been used on transplant recipients for ' side only several years, its long-terejects are unknown. Researchers from the Mayo Clinic, where arthritics are being experimentally treated with cyclosporine, cautioned during the rheumatology symposium that the substance can be considered only for patients with vtry active rheumatoid arthritis who hdve not responded to traditional treatments. The suspicion that arthritis is caused when cells in the immune sys- - 1 mnrfTnrr "t 'f ' TT After Christmas alt akf K DIAMOND JUDILfc f Cannon. the U. of U. School of Medicine, contributes to a better understanding of t heumatic diseases. Dr Cannon believes the real "breakthrough" in treatment "will come when we understand the cause." Until then, he says, science will be unable to either prevent or cure rheumatic diseases SSCHID 1910 mrrTfrr Pain - Hopes to Research Arthritis Treatment By Anne Wilson rr A g3 furniture compar.ij UTAH'S LEADING AND MOST PREFERRED HOME FURNISHINGS CENTER FOR 75 PROGRESSIVE YEARS. k I I Salt lake Citv lOSOfaK At the Sugar 21t South Houia Provo 1134 North Sth West North of Utah Valley Hospital |
