Show f Scientists Synthetic Dev Develop Synthetic Frogs j 1 r f In Order r to Study Study- J Gland Ep Functions i i Jt to J 3 By DT HOWARD W. W nL Press Science Editor f BUFFALO Nov Frogs Zo 20 Frogs which Web t ere are re synthetic are grown at the University of Buffalo They are altered In earl early cAdy youth in the gc by having their pituitary glands transplanted rit by an an e operation to another part of their bodies bodles from r m the normal location at atthe atthe the e b base e of ot the hc brain Changes Changes' result In the frog some somes s s and and Visible bl oth others other's s 's wholly i In Internal But tut all scientifically Important tant t nt and and ot of potential value to lo man Fo pituitary the Is Isone Json one p of th the endocrine endocrine endocrine en en- stands glands ridi and m ts s s. s beginning be- be ginning to how h v itself as the master gland gand and of of- the endocrine system It It It heads heads' tip up the series aeries of ductless glands Elands which are arc rc Intimately asso associated associated with growth ow h. personal appearance appear- appear a ance ce l insanity sexual cx al development development devel devel- vel al arid amid indirectly directly probably with the emotions But the thc p pituitary is is' difficult to study for tor its system of control is complex Transplanting cuts K J of the glands gland's Js J's 1 functions so that those remaining st std nd o t clearly Thus S one one by byone ne some of the vital endocrine t n on are Isolated and studied by Wayne J. J Ph D. D professor of im anatomy Th The gland Bland nd which he transplants Is the size of a pin head hend When removed from the head and grafted Into the s 's tail the gland loses most of Its potency The tadpole can can- I riot change Into Into Into-a a it frog that is' is cann can can cannot n not metamorphose But if the pituitary Is transplanted transplant transplant- ed cd to a position near the tadpoles tadpole's Inner hiner ear ear car he hc metamorphoses into a frog CHANGE IN COMPLEXION He also turns turns a silvery very color instead instead In Instead in- in stead of the usual sual dark green This c complexion chR change ge Is traced to atrophy atrophy atro atro- phy of one cne of the sections ns of th the transplanted pituitary the Intermediate intermedIate intermediate diate lobe Little i f is J known nJ yet et of f this lobe lole but butis its is Its effects on at frog coloring h have ve been verified His c color or turns urns dark again if f he Is Is' given extracts of this this' lobe taken from other other- ari animals When the extract is dJ discontinued coni u d. d he Ji e becomes silvery silvery once once more Not all aU of the transplanted gland withers T The Tice e anterior lobe which controls growth gro and the w welfare of the tha thyroid and the sex glands all of ther members of the n well In its its' new position |