Show A22 — The Herald Journal Logan Utah ammaiDs moire ceminniein) fount irooti COenDDinig Wanna i cow'1 A Massachusetts ' uiiiuiiv giiuiuiilces a liculihv oil loi Spiomr and two lor M i lone ' ()I"K V Thusday November 27 2003 us that can make anything" I'ihelli said "Not all the genes will lx? ready to he repro- - l’i i graninied' " sUj'nni iiuiii clone a cat'1 A Cali ' lorma kised company says it’s ' 'gearing up ip viler dial service mm uk niavk next year Vmna done a cute monkey? v(MHl:liiek Almosi'veti "years alter the ' 'miliiil loK die sheep ' sluvkeil scientists and (ay peo-pie eloiiriia lias sin nyn mixed !v'r ! progress Scientisis have ' achiev ed il in more than ii' liven liiamiiial qxvies from V' 'nice hr rabbits goals pigs and say-Tha- ' ‘ k ' ‘ ' 'lioisos-Tlie- 'vetliined ycalf y mlitered cow ’ ' If the changeover isn't com-- : plete enough the ’egg and resulting fetus just won't he equipped for developing nor- t can mally scientists dixim a pregnancy liven in animals that make it fiyhirth faulty reprogramming : could lead to observed ahnrir- - '' iiialities in clones like hreulhjng problems and defects of the liver licart and brain Some abnormalities may also due to manipulations of the embryo kfore implantation! Despite the appearance of defects-isome clones scien- - V ' " ' ' ' lists point out (hat many animal clones turn out just line “We have seen cloned cows that are thriving at the moment and indistinguishable from animals" Ciklli- said Slice said that's ken the experience of his clones "The vast majority of them are ju st fine" lie said "Tky lxk like runy other pig or cow out who made her birth possible She’s an "absolutely normal ' cat in every aspect we cun determine" Kraemer said She does have a heart murmur like ' the cat she was cloned from ' Neither animal has hud any trouble with it Kraemer said ' ' Scientists say tky hope to achieve cloning in more tkre" Species Mark Westhusin of Visitors to a home in Texas! ' Texas A&M who directed the K research that say roughly the same thing produced ec said ' about a calico cat that frolics k's trying to clone white-taile- d ' deer to tkre It's ec1 the domestic kip ranckrs who sup-shorthair who gained fame in ply game for hunters' White of' Utah State hopes to clone an v February 2(X)2 when she was ' announced as First clone of lk endangered wild sheep called '" a cati'This year she moved in mas- -' tk argali known for its ' : "'with Duiuic Kraemer one of sive curved horns non-cloii- ellicicnl cloning process still eludes them' ' AP phdto t 'lones are more prone to phy!v ' Ihiin ' ' aniiciil delects 'regular The cloned cat'cc relaxes at home inCollege Station Texas' Aug ' ! And researchers £ in I llw injujViire ''4 The domesticshprthair who gained fame February 2002 when ''haven't been able to duplicate her birth was announced as the first cat clone pow lives with Duane" V -- uiii'nkevs inun adult or fetal tis- Kraemer one of the Texas A&M researchers who made her possible medMie a goal that could kip Get in tiiolher where it grows into a1 nucleus of an adult animal cell icaf a’sOareh" holiday mood and enjoy — I n Nu new an clone these over tk genetic ednjd Undergo biologiliivering umaing classic clips Including Andy's solos of lheunimil whose DNAyou cal challenges are two oilier eareerehahge Al'terall ilsjoh slarted!with had the drive to Fixxl and )mg ken issues Tk every day “Silent Night" and “Ave Maria1 ' An egg has its own nucleus activities of an adult cell w illv dmhiistration is ponilering the certain genes active alul (ithers vsv tliat lias in removed as well as performanceis with Safety of consuming mealand sw itched off io achieve that before the egg receives tk new milk I P up clones and their the Osmonds one Normullv that dixisn't goal Bui once il was placed in piVgeny a iiitlter of ohvioiis it had its inonBut with a !’an to ranchers conienito feprograit'i pose problem ' egg jiiixmanee ' gene activity to start the pkiiing cloned pigs aiid cattle keysit diies' t Sehattert's kieiiti lie team 1'lic I I )A recenllv said siich process of creating all tk'tis-- ' ha- sues of a w hole new' individual liHid ikx'MVt itppcir to reported earlier tbis yeaf that ''If you hiive a nucleus iliut 'irdiiiis biil the agency wants'''- - removing tlie nucleus from a' ' University of Utah lius also eiininwhl Because ken committed to skin remiivestwo nuire egg monkey public ' ' kuccLorg of a voluntary' iinlustry iiiorato- - key pniteins Witluuit them the for a niimkr of y ears tkii In a ' jnaitcr of minutes ii qhahe'e have sUuul to divsii't rium: no prixiuets frinn clones tf egg yoii have k-C- allowed inUi the ' turii H into ah enibrysinic inicle-''fixgrowing into a new monkey " ! S'challcn figures this problem supply 'And tkbigjiot button rrlhq will dvLfeoikandkvv'txiiji monkeys w'ijj eventually fol- prosped of making huiiian iiiibies through elonjug-rlowAndhe'sphiliisiipliic'al stilly: ': labiiut' bumpiiig into "the hurdle-- ' gloyv s Would that present a ' ' in the first pjace keaklhrough fiir treating inl'er " :"I feeflike naiure hasgive'n (ilitvandpriivide piirents a r' usa scientific reprieve" to " v' ''gcnolic duplicate ofa deaif cliitd ’ifr would it bl‘ck human climing with eur- ethically' to s repugnant and unacceptably r tent techniques giving time ' ' " Vjrlaws hc'suid': i'isky?:-develop : : " With bamvard animals fiie United Slates teeenliv r' AnfV WIIIIgIIIS D6S( Ol niKly I'fillSntvf fir Christmas Shows the k Tonight at 7 KUED? k k n ' xl k - v k ' j tofe lent forus Uiiited Staled 'alsrfwint isVJhen wt "hiTdpcmicPlhat embly()'andwitdl)nt'prt' i industry wimT use stem suchiflnessev lV!inwliile- - C ' five babies tlifoygh cloning !Vvgrahkd headlines last 'lXcemkr by ahmiuncmg llie : llrst siich hahy hiicl ken brim but that clainvhiis ken disr missed by scieinists for lack of" ‘ - k ' - - Mosi scientists who dcd with cloning oppose using it to ' make huijuin babies "1 luman repniductiye cloning is unsafe ille- unelhical and ought to gal every who rein the world" ' ileclared Tierald Scha'ttenof (lie ' v ersilVof Pittsburgh Schatten is tJrise to tk debate kcause he:s ken try ing ' I ab CIi iiiiild pnxif:- ' enoiigh Chiniiid'acomiv: Vb Ib f " Ia t kh in ? ' - dis- - ’arkinson's inierested k elTictenl iit producing newborns'? llxH 29 implanted! embryos Ckall lla aVl 111 'abMal llMd s MiChigah State Uniyersity In cattle these days dnly one ! "' in seven to one in 15 irons-Jetted embryos produces ilk ' : ' spring Stiee said Inc Worcester (if AtGyagra ' ' Mass' which has prixjuced l more than fXfealf clones for dairy anil kef farmery market- - ' ing manager Steve Mower says the track record is about 15 per- Cent : "We have to do ktter' he ' savs and ihe criinpapy is aim-t'- ni ing at effiejencies offiOpercenl tir l(t perceni It's not just cowsIi tixik l 13 'whichiniplanled embryos to pnxluce loclonemonkey to tk same overall ejas- - just three cloned mules this -- ilicatiori — is ' ' year ah efficiency just klow 3 ' primates liumans Tk implications of percent saidone iif the cloners Keti White of Utah State Uni-- ’ m Success for lk prospects of ' '! luiman cloning are clcan and ' versity 5fchaticn said hit's already Ti deal with efficiency ' exploring ways to make sure jpniblem some scientists are raw materials lhit it he succeeds olkrs ' scmtiniing able to usehivwork anri't Itxiking for wavs to identify the most promising eggs and the " 'opn xlucc human Hahies Schaiten w ants to make iden- -' ksi cell nuclei from animals to cloned Ciklli for example tical monkeys for medical is kxtkihg forckmical markers reiarcb pnividing a more bunian-lik- e that can identify a nucleus version of the': that's ready to introduced genetic uniformity fixind in into the egg mouse strains But so far! his cfiorts have failed even to pro"We're getting gixxi duce a pregn'incy What's results" Ciklli said ’ InfacL many scientists going on To' understand tk apparent nuc leus of klieve donor cell holds the kev for you have to know a lit- tie about cloning Tk basicwhy cloning works so sporadic DNA-karin- g idea i to lake cally as well as w hy dimes show unusual rates of birth nucleus ot an animal's cell and defects plop it into an unfertilized egg For scientists Dolly Tk implanted DNA drives sheep was stunning because egg to develop into an embry o which is placed in a surrogate sk showed that the DNA in ' : ' tk tk k k k tk tfVgSnV lk in-w- er - M&it iwgji tk lk tk tk V - — I" If (Ml lii Ssv ' '" But-a- f easy the Texas A&M researchers on - |