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CAYBdp 938 +02 * 22 +54 388 410 103 «78 ‘02 SBT243 da]“18! Sane te 148+ om 831di|"memeemes5 Saete 2070 a oe139 SeGAp M81 Gooey 4404 +82 ay] "221 DNICAP Dosage: Patients Like are wasted because people don’t take all Longer Lasting Drugs Among other companies developing Jonger-acting drugs, Eli Lilly & Co. this their medicine. spring is expected to apply for FDA approval for a weekly version of its top- from D-5 ‘shot instead of daily “is the big- antidepressant Prozac, now given once-a-day. Merck & Co. is awaiting FDA approval for a weekly versionof its once- on weekly drugs to treat anemia in logy -at the University of California. will all oftheir medicine if they only need one dose a week, meaning fewer pills will sit:unused in medicine cabinets, leading to a rise in sales of refills. Companies also are expected to be able to charge more for the newer medicines. Prices have yet to be set for the new series $80 s128, f, iS 12 212) Sotecn 68004221 579) tn 18 Maun 1858 Faincmn 10.00 +02 +09 +01 GiSeAp 241Ce aa ‘Specin Srp 279 %50| Doce 2090 +17 08| Gee Iau t05 a Lord Ab et : BaoCp 899 +03 Lutheran Bro A: Brot 810 +09 +43 Find 2898 incom “808 04 Moe 831 sor MASFie Ck: mepeipsin oe Fesnat Ct: Eqayn 1729 +25 Faden 1082 $05 S054 +84 De 4548 471 4 Dn 5383 +11 Dvind 800 $08 40 417 +01 <4 659 38 02 Fedsecs 208 11 404 ‘ ots x a8 05 138 411 “7 31 2 +09) aaa ae stealae[28| Os] MeapvAnaist SBP in 2220 STBdiden 951 31 emanates ") Eee IE, tor 2 32)3 Age 70 +18 3s gost ‘es 1509 3.11 a 484| 485 492 38) 07 08] 83] 402 13] * St Dean Wit B: Sesoos + ‘das 8 + me oreo 12 38] ‘ScudderFunds: "Guanes + 7045 +116 425) Oewin 48:39 + 9) Godin 31.18 MaCoA500 +89 +39] Geoen Mas +81 GreuGrn 2843 3767 +25 +93 UROTCIN 7 11428 4723 +130 Groin” I incomn 1224 4.02 domz 2615 +57 +35| imran 6957 +109 Shidin 3198 340 10] UgcoGron aa47 "+85 Shitez 3196 +39 10] Lpcovain 2571 +07 Inez 22.00 +04 34] Litany 2700 $31 Fed A: MATen 1335 $01 “G2 )"Saumap 1218 +05 -16| MegTrn 1073" a 1538 | a . 47 460] “12| 407] 432) 31.1] “38] +41] 303] 03 Kamp BA 582 438 Cmevp 10090020 1419 “02 EGAD’ Erp S47 Eqnchp 7 0 504 GySeAp 950 $05 Girp 1788 +07 Hap 2242 562 HopAp 584". HMAp 10a oi soe +33 “45 487 148 +10] 713 ‘02| +68 to2 03] 401 Gate 1 B58 +416 SMOG 3537 428 WilamSCp 1926 +58 witam Bla: GroweN 2048 +40 wan ee LOCoGep 4339 +67 in 8S Fata receiving chemotherapy and “History tells us the drugs with the better formulations that are more patient-f ly win hands down,” said Steve Arlington, head of pharmaceutical research at the PriceWaterhouseCoopers consulting firm. Drug companies have been able to longer-acting medicines by using higher dosages and altering the mechanism in which the medicine is released into the bloodstream. Still years away is the development of once-a-lifetime drugs with the help of aTarts efso ooh Watptee fall ay +17 452 «81 118 5 +0 30cet eet, ee| Ores tS“ Ge Sean oe ol ere ap tee,t am 118 618 si] 10] TomBt 1342 222 405] Geonp 2500 <8 69] Smoovepriez -0i 49] Paoadp 1248 511 “15 Fandpn 850 -08 43 the need for medicines given less frequently. “Insurance companies want to make sure people take the drugs they are paying for,” said Stephen Tang, a national director of A.T. Kearney health-careconsulting practice. Drug companies have some experience with drugs takenless than once a day. For example, Pharmacia & Upjohn makes the Less Frequent Doses Here is a look at four top-selling prescription drugs that will soon be offered in longer-acting versions. injectable contraceptive Depo Provera, gest new developmentsince the develop- ‘companies believe more patients A178 Soar ot aw vm at #2) coagmet"1175 +082)+26 organ BS Ba 1: | Seofg B oe | Rea n ce 4: Meet tn ae ae 4) Get, am 2 | omitee 2 Seeaa 221 +: BaPen” ;‘2 +43 DeGAp 2080 +18 08 Node Mate00 ee 407 SITFBdpn 989 403 Bond ten an so Eval eat 237. 3 a Hospital Los +42 139 13 of 150 S75 Gibircn 2547 +31 +02 7 | Mainiay Funde A: SMORGRI Seine 1 2 : 04 624 02 Smith Barn Comat. t Bees o "| See Baie| aes ag <e | tate, ee cm | eee, aoo aH bees Ue cet 3a Se, ae 28 inSmcB 10 Techie _ end ip Gene oe P10 +54 439 Shap” 2256 335 503) Fda nSMOA 42801074147] Techn 5821 41374192 "iq 2560 423 10 403| Lou “980 MuSecA USGWA 967 740 +01 400 04 M909 +08 27] hae 13 18 $oGen: Cen 283 +40 18 HinBaA 1029 -01 eae satelite ae alae imex RBA = 202) 104 15] = ¥ #83 “GS] +28 09 oat ot +85 339 352 112] iniGon 1886 525 s13| Equty 1468 +09 00) Bondan 1891 +06 +05 Phoenl-Oakhuret: +52 +19] Smooaen 2022 $25 326 Mere Egon 2372 429 “10| Salar 1742 +18 04 EGA 2539 +64 4145 USLgCp 11.99 +19 -1.3 Nuveen Cl A: leGeAp 9.64 2 Mergora 1511 +01 <21| KYMusp 1030 +01 «07 Phoenix-Seneca: Merril Lynch A: QHMBAD 1083 304) MdCa0A, 2867 +45 +56 BAVA 3858 + GisAp 2512 +22 -14 Phoenl-2walg: A S87 UMA 1036". 401] MOAT ‘ 880 4+ ‘NuveenC1: Siar 1371 1105 +08 +07 +02] “0s 1081 4 Wann 1022 +01 43.0) Plgrin Evoat 1385 + towed880.01 307 evapp 1563 1581 +13 at +19] 19 Funda at 4 ‘yest Funds A: GINAT 1382 +. 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St 2k :2 mia s3 ae oa 8 aD frecs a7 preot 677 365| Senet $25 ‘Consay a2 Bt 3 iz My 2 ae = ip 1Sat “ os 4 ) Gowar 1199 21| Seomp “Tas 2 FNUAR 1428 + faeat 10m > weap BS +5 372 333] Gaeeake moe 3 8 i wt Ae Woe coe Be ws meen 33 22 wavA i246 Sop S07 #14] PAAR 1753 314 24) Geter 971 Santee 17 ee sa ag;| MYCaprn 728 «ot +33 gkeb, it te 1532 oOo -15| MeCwnALI +43) 10 Yh BAR : * soa) et fogs 2 7103 tocpaBe 1635 + 5 2 W Ree ae oe | See renee Aout B72 EqSe Evel eat Fed we a8 oz en i}: 2S ‘ge|38 SookeSe HE tale wep aly hw 2m co3o 22] eon se ne erg wes PendA: t am 0G 2 nw GR Pane Be +m 28 suse ar | node 4 Rees5 Tm om ne ft vem +m a3 am «a 42 ne. 4s az «i } i which is taken once every three months. Though Depo Provera has been used in the United States since 1992, sales still lag far behind daily birth controlpills, Analysts say women don't wantto be bothered going to the doctor'soffice. But injections at home are a convenience for youngsters like ShannonCollis, who gets a shot of growth hormone every other Sunday night. Collis said ifshe had to get an injection of the osteoporosis drug now taken daily. “nee BB dem = rey Siamoceststres” ae Genentech won in December U.S. approval grown,” she said. “The shots kind of hurt, wee it every a growth hormone. Injections are now usually given daily, |
