Show Mania And Depression A challenge to the commonly held theory that depression and mania represent opposite poles of a single biochemical continuum and a description of the little-understood between the conditions have earned three National Institute of Health scientists the coveted Hofheimer Prize for THE PRIZE is given by the American Psychiatric Association and was recently awarded to Doctors William E. Frederick and Dennis L. Manic depressive illness is second only to schizophrenia as the most common mental illness and is also associated with a high incidence of An estimated Americans are now under treatment for severe ONE particularly striking form of main-depressive illness is seen in patients who vacillate between and euphoric behavior and and often suicidal behavior The prize-winning scientists found that the switch into manis is often preceded by environmental that certain drugs are capable of inducing and that certain physical and changes accompany switch in IN their pioneering studies have advanced understanding of the role of brain and nervous system biochemical transmitter stances in manic-depressive For the investigators point out their findings that the can activate a form of mania in depressive patients without helping the THIS SUGGESTS they that mania and depression may be simply opposite poles of the same abnormality but may in some separate carrying an honorarium of was established in 1947 in honor of Lester N. Hofheimer to honor U. S. research investigators for outstanding work in psychiatry and mental THIS the group shares the award with Joseph J. of who is also a leader in research in the field of and depressive |