Show ' CIO— The Herald Journal Logan Utah Wednesday October 8 2003 Supidl toy to FALMOUTH Mass (AP) — The ot squid boat takes a gentle turn toward a Woods Hole pier on a summer afternoon its nets filled with an animal whose primitive nervous sys-te- fn holds the secrets of the human " Loligo’s skipper watches under a hot sky the squid expelling jets of water as a deckhand scoops them from the boat for transport to the Marine Biological Laboratory just a few hundred yards away From the time of delivery professor George Langford knows he has a few hours tops to get his squid dissected so he can continue researching the mysteries of how the brain remembers ami what makes it forget when a disease such as Alzheimer’s takes hold For 3 1 years Langford’s studies have revolved around squid nerve fibers called giant axons that are several times larger than a human’s and offer unparalleled opportunities for observation and experimentation The squid axon is so useful in the general study of nerves that some joke the squid deserves a Nobel Prize for its contributions to science Langford’s progress has been quiet and steady over the decades as he seeks no less than cures to various degenerative brain diseases It’s part of what drives me in my research” the Dartmouth biology professor said "It’s really understanding the basic process that’s going on and using that information to try to solve human diseases He added “It takes a long time” Langford’s Woods Hole lab is on the third floor of a nondescript build-in- g that overlooks the harbor and its steady traffic of fishing and research stodly can link with other cells The connections also depend ein ipackets of The hallway is lined with refrigerinformation pushed within this ators filled with the chemicals used skeleton by different types of “molein various experiments Just down the hall a Spartan loom houses the cular motors” j A malfunction in the cytoskeleton equipment that Langford’s studeht research intern John Delacruz uses during these cqnnectibns can cause to remove the squid’s giant axon! If problems such as a loss of memory the squid aren’t dissected within 10 So if Lhhfeford can identify foe proteins in foe cell skeleton he can tell hours of delivery they bang themselves against the holding tank walls : what proteins are pitW or absent when foe motors aren’t delivering so relentlessly that the giant axons information properly are useless The squid’s giant axon is essentialEven if all the proteins working i fibers a nerve of bundle that the cytoskeleton can be identified carry ly electrical impulses to a muscle that Langford’s job wouldn’t end tfiere contracts and propels the squid “If we know what the protein is through the water you ultimately have to show how it functions" Langford said “You can Though the human axon is much smaller more complex and carries say this protein is missing and it causes loss of memory (but) you the signals more quickly at its base still have to connect the dots” the systems are the same and whars learned in squid can apply to Thomas Pollard a biology profeshumans at Yale University who nas sor ) worked with Langford at Woods “It shows that as all of us evolved Hole said Langford’s most imporcertain basic functions have remained constant from the smallest tant contribution has been his disanimal to the most complex” Langcovery of previously unknown ford said “That’s one of the princimolecular motors which seem to be ples that brings all of biology part of a network that carries content shorter distances within the axon together” Scientists know squids remember “It’s like a transportation system" — the animals recognize predators Pollard said “Before George’s and even respond to shapes that look work people had focused on sort of like predators the interstate highways and his work shows there's probably a local transThey also know a squidVbrain like a human brain is “plastic” portation system like within a city” like a d Without an awareness of this secmeaning it’s not computer Rather the connections in ondary travel system scientists ' foe brain are changing constantly as could never completely understand what’s happening when connections messages are carried by molecules and stored break down he said For those connections to occur the Langford’s work takes endless “skeleton” that helps the cell keep experimentation using varying levels its structure — called the cytoskele-to- n of chemicals in different concentre- ' must change shape so the cell tions and over different time frames vessels 75-fo- brain bcaiDmi ii Y t&tmm ' hud-wire- - AP photo : Squid are shown aboard the Loiigo fishing boat before they are delivered to scierv tists for various research projects at the Marine Biological Laboratory last summer Thanks to you I v A Patriotic support appreciated- V v To the editor The Celebrate America V : committee would like to thank the following businesses and V‘ people for their support: ICON Fitness Spillman Technologies The Kata’ Shop USU Cache County School District North Logan City Cache County Mayors Association The Herald Journal Cache Valley Radio Group Logan City Davisco Xerox 'Lee and Yvonne Roderick USUTSC ASUSU Zions A Bank USU Community Credit Union Square OnePrinting Smithfield City Hyrum City Junction Magazine ARS Advanced Restoration Main " Street Autoplex Lee’s Mar- ketplace Scott and Michelle Watterson Pallets of Utah Brenda Anthony real estate PC Thomson Premier Lighting Cache Chamber of Commerce Truss Tec LeGrand lohnsdn Construction and TEC Electric This program would not be ’ : : Lee’s Market Place Bert’s V Cafe and Grill Wolford Auto Body Steven’s Chiropractic Jane Larsen’s Allstate Insur- - ’"i munity- - Boxing program V ance and WestMotor Thanks to sports page of The Herald Journal for foe coverage of the Hyde Park boxing competition This allowed news coverage letting the public know of foe club and the come back of amateur boxing to the Valley Thanks to the people attending garage sales and participating in the Casper Fund Raisa event This money all went to help buy muchneeded equipment A special thanks to Brett Downs for his donation that helped buy competition head The Elite Boxing Academy To foe editor To the editor V : We would like to thank ' Logan High School recently every one that has helped foe held its Homecoming Week Elite Boxing Academy get We would like to thank the started by attending our box- " many businesses and individ- ing matches held in Hyde uals who contributed to and Park and Logan this summer f We would like to give special helped make the week a suc' - thanks to foe cess Businesses along main sponsors of there street helped students bring events Without them the new box- back the old tradition of : 'gear “painting the town” by allow- ing club could not have pre windows us their the boxers Boxing competition helps to sented in young ing paint the The police department youth participating in the Some of our competition club to gain experience confi- helped us organize activities sponsors were Trail Ridas - Members of the Inc G F Productions Crumps community involved came and to the Motors Alvares Fencing Fly-Tegot activities that were held with Koby Guaranteed Thank you to the many pco-- Preston Auto Body Auto Care Garza & Chamber’s pie who help keep the traditions of Logan High School Paint Repair Cycles & Sled Cache Valley By Products strong We hope to he able to Cache Valley Advantage Auto keep them going and continue : ’ ' Penning sponsors thanked 7 ch mm indoor Theaters 2297 N Main MOVIE HOTLINE 7IS-M4- (MOBHBMU ft2 11:45 aw Rosie 4 M4IMBB laid ! noa mere ico INVEWMOO 43S7MMAT122S2JI MHIUMIIWM Ballet West s Giselle Jonas V KSge-Arti- Director stic A timeless tale H) POG'OW oflove and betrayal Byron and Diane Andoson Founder’s Day Team Penning UTAH ADULTS 752-307- J300T 2 $200 CHILDREN mrocht Yalh' LuxunM SOUNOB GREAT GREAT SEATS GREAT RICTIJRE FINDING NEMOm nasEBomiBa WEStATES THEATRES WtaL Dhnri Dty Al Shw $AJO BiyTidabOlSnailwMmnMEDlaOiKlnuam Hot In LOGAN ARTCINEMAi 795 North Main American Splendor 7X STADIUM 8 L afeaarf" i t— 4W7JiBMWttlll9i UIDMMaUf&IS 1S TiiKvrgr system and friendship circle” “But not a campus club” interjected Henderson Sap-pho added York is a group now more “cultural ratha than politically active” Rosie was formed to be 'more inclusive and to fill the need for a politically active women's group Henderson said Rosie's first action item will be changing the university's custom of having foie blue A on Old Main lit only for men’s football and basketball While noone in Rosie belongs to a USU athletic team they ' believe the 13 other sports played by USU students deserve recognition They and more than 300 signatories on a petition want to see the blue those sports teams A lit both men’s and women's Henderson said if we look at foe history of US civil ' rights each generation sees another minority struggling for equal treatment and acceptance “This (gays and lesbians) is just a different minority that has to cross the bridge" she said ROSIE meets Monday evenings at 7:30 pm in the Taggart Student Center room 312 Anyone interested is welcome to attend Elwood (Wellsville 4-Kristy Kendrick Jake Downs Ralph Parka and the riders Wifo everyone’s support and : help fois year’s team penning was a great success IKMJONMriMGOO Ml W MU 031 29 IWMEMUUNICn Ellen EcdeTneatre Presents Cl Bankhead-DenaDem- To the editor: ' We would like to thank the -following sponsors who have ' Wellsville the supported Founda’s Tram Penning for " the last five years: Griffin’s ' Feed Gossna Foods Steve Hancey Intermountain' Fanner’s Association Kim and lisa Mendelkow Poulren ' Trailers and Wellsville City Also a big thanks goes to foe individuals behind the scenes: Mrf OfRNMNimcia Continued from - Evan ' kr Austin Demia Joanne : : was a hit a great tradition dence and reward for the hard work they do to practice The boxing program helps foe youth participating become physical fit gain self esteem and fellowship with others 'v Logan High School Student Body Officers Celebrate America Committee Homecoming i to build Grizzly pride in the school as well as in the com possible without foe generous support of these sponsors Thank you for your efforts toward quality patriotic enter- ' tainment for our community 535 W Pravklanc TOO tsl Roclc ro-School Of vjtA too na ms n NktaMoMMMtrMM Tfio ss-- i Rundown ' 3 7:03 f:2fl Underworld l:SO m 7W Out Of2:00Time 4:23 ro--i or OfcMMHf SJO 13 rteirnm bond SecondfeOO lions roi 4:33 74W 33 PirafM Of Tho ro-Coribbeon 1:30 4:10 730 9d0 Tho Book Of Mormon Movfto sa UO DuploX Me 4:30 738 :43 ' ap Ahm or Chwnmt Hrfm 7100 MOVIES 5 2450 North Main School Of Rock ra-J-t S'IS 7:10 Out Of Time ro--i 7:20 NhfkiMerniMMMm Cold Creek Manor ’ m 4:30 74)0 9:23 Tho Rundown Duplex rs-v- e 10 425 70S MMwVfMUl Mi Wimi Cl fa I a XJlJ1 Wm- Wednesday and Thuriday October 8 and 9 7:30 pm Ticketst S30$26$20 (Olnuililiit - 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