Show lr nr i Page 4 — The Herald Journal Logan Utah Wednesday November 8 2000 Gene helps patients respond to chemo By Lee Bowman of patients with the altered gene had a significant Scripps Howard News Sendee response to treatment compared with about 36 percent of patients who did not have the mutation “The most exciting aspect of this research is that we can begin applying it to therapy right away" said Dr Manel (cq) Estcller a research fellow at the Hopkins Oncology Center and first author for the Scientists expect that standing the genetic makeup of each person eventually will make it possible to treat ille nesses with drugs But in the meantime researchers are already finding that some patients have “custom" genes that make certain drugs more effective for them Doctors at Johns Hopkins University reported Thursday that some people with an aggressive type of brain cancer have a genetic mutation that makes them much likelier to respond to chemotherapy They found that 63 percent tailor-mad- Medicine was based on analy-m47 sis of tumor samples patients with glioma They had all received standard treatment with a drag called carmustine But 19 of the patients had a gene called MGMT that had been altered through a chemical process called methylation They were much more responsive to treatment with The discovery reported in The New England Journal of 2000 in the Richmond City pjn Friday at Webb Funeral new drugs to be developed rather we can begin more effectively tailoring the drugs 'we are using today" the attack tumor cells unchecked eventually find agents that might block the repair function of MGMT and increase tumor sensitivity to carmustine Obituaries William Matthieu Cemetery Friends may call from 10:30 to 11:30 am at the Alien-Ha- ll Mortuary Friday Burial will be in the Richmond City Cemetery with military rites by the American Legion Robertson 7 EL PASO Texas — William Matthieu Robertson 68 died on Nov 3 2000 at his home in El Paso Texas East St in III ' ' ’ Regional Hospital A complete obituary will follow in a later edition of The Herald Journal MorArrangements by Alien-Ha- ll tuary Logan am Saturday at the church in the Preston A complete obituary in a future edition of Burial will be Cemetery wilt appear thepaper ' Death notices Niederhauser PRESTON Idaho — Robert Margaret P Hobbs PRESTON Idaho -- r Margaret Palmer Hobbs 84 died Tuesday Nov 7 2000 at the States Postal Sendee He was an avid golfer He is survived by his wife of El Paso Texas a son Allen and his wife Michele Robertson from Wichita Falls Texas and three grandsons ' Franklin County Medical Center Funeral services will be at noon Saturday Nov 11 2000 in the Preston 7th Ward chapel 155 N 200 West with Bishop Thane Goodrich conducting Friends m y call from 6 to 8 Graveside services will be held at noon Friday Nov 10 Obituary policy The price for obituaries and cards of thanks is $4 per column inch Obituar- -' ies are measured columns wide by inches deep including photographs All obituaries must ba placed by a mortuary or in person by someone authorized to make payment or arrange billing There is no charge ' for death notices placed by a mortuary For more information caH The Herald 1 Journal Niederhauser 65 passed away Tuesday Nov 7 2000 at Logan Regional Hospital A complete obituary will appear in a latbr edition of The Herald Journal Arrangements by Mortuary North Logan Utah Alien-Crann- Edna LaRae Burr Hansen LOGAN Utah — Edna LaRae Burr Hansen 86 of College Ward Utah passed away Tues- - 752-212- Selected stocks stock prices are quoted and fractional dollars per' share Mutual funds are quoted in' dollars and cents Mid-da- y in whole At approximately 9:30 am today the Dow Jones Industrial Average ' was 1098631 Albertsons American Finl 2412 21 316 - AT&T Autoliv Iric 22 1516-223- 8 Boise Cascade Campbell Soup 301116 30916 - Citigroup 521516-1 Conagra INC Edison Inti 2212 NC 221516 14 90316 Exxon Mobii 316 116 12 69116 53 38 5734 Gen Dyn Gen Electric Gen Motors Gillette loacorp -- 38 34 18 11 91 116 212 ' '18 38 -- 12 -- 24316 35 1316 Micron Microsoft Starbuckq Telegiobe Tyco Inti " 14 38 2116 1 1116 Montana Power 27 131 6 NC Moore 21116 116 ' 316 Novell - Nucor Oracle PG&E 516 57316 Pharmacia Corp 1 18 116 716 516 - 4838 38 026 FDCAX 2643 Magellan 13181 012 058 Bond-Debe- 785 660 1677 1824 i Lord Abbett Affiliated US Govt 14 3291 2829 New Perm 3075 Gold US Govt World Growth Viacom 58 12 - 716 WalMart 49 14 14 Wells Fargo 4618 - 38 Zions 57 2132- - 732 Selected Mutual Funds NAV POP American Funds Group 1963 008 Amcap F 3707 004 Europacific ICA Wash Mut Fidelity Invest Franklin-Templeton 561316- - 1116 : Union Pacific 178 7138 316 316 2818 4558 2358 3018 3012 3014 4634 24716 Qwest Reeboklntl Rohm & Haas Scottish Powe Sears 916 116 6 15 516 Lucent Tech Merck & Co 1316 25 516 34 38 38 1021316 Kmart 316 Ford Motor Co 35 1116 614 JC Penney 35116 Philip Morris 116-51- --- -- IBM ' Agendas The Hyrum Planning Commission meets at 7:30 pm Thursday at the Civic Center 83 W Main St Agenda items V include: Approving a site for a rccrcationalyouth center at 230 W ! ' Main St Approving a taco shop at 103 W Main St Approving a conditional-us- e permit for a retirement planned unit development at 100 Noth and 300 West Discussing thegeneral plan VThe Logan Planning Commissiofl meets at 5:30 pm Thursday in the Logan Municipal Chambers 233 N Main St Agenda items include: subdivision on 600 S 1900 West The Considering a two-lcommission will discuss rezoning the property from agricultural to recreation subdivision at 125 E 1230 Discussing a request for a four-lNorth for the proposed Marketplace SubdivisionHome Depot ot About Cache THURSDAY Parents of children with special needs are invited to attend a workshop with Judy Jensen education advocate at 6:30 pm Thursday at 1 15 Golf Course Road Jensen is from the Disability Law Center The Cache South Company of the Daughters of Utah Pioneers will meet at 2 pm Thursday at the Mount Logan LDS Stake Center 563 E Center St Gayle Miller will give tire lesson Logan Nursing and Rehabilitation Center is having its monthly family buffet at 12:15 pm Thursday This is for all family and friends of LNRC residents The Logan Parks and Recreation Center is having a ribbon cutting ceremony for the new recreation center aerobics and weight room at noon Thursday at 195 S 100 West The public is s' invited - 3413 These quotes were taken at that time and1 provided to The Herald Journal by Edward Jones I ot Robert the son of Samuel J Robertson and Ida Belle Manning He married Ruth Allen of Cove Utah on Aug 4 1962 in Sedlia Mo He served in the United States Air Force for 20 retiring in 1970 Following years ' his retirement he was the director of customer service for the United Louis ’ He was born 1932 March 28 day Nov: 7 2000 at Logan Home and from 10:30 to 11:30 A Niblcy man reported to the Logan police that he was struck by another man while waiting in traffic Anthony Merck told police he was waiting for the light at 100 East and 400 North in Logan on Tuesday afternoon when he looked at the car next to him and the driver made an obscene gesture When the light turned green Merck said the other driver in a ami parked his car Because Merck Dodge track did a was still in traffic waiting to make a left turn the mat) came over police said Merck said he unrolled his window and he and the man exchanged words Then the man reached in and struck Merck in the forehead with the palm of his hand police said Police are investigating U-tu- rn Methylation has long been known to act as an “off” switch in genes And it has also been found to play a role in cancers of the colon’ lung neck and lymph nodes But more research is needed to confirm this mechanism in the brain tumors The scientists also hope to most having their tumors shrink and as a group living an average 13 months longer than the 28 patients who did not have the altered gene The researchers speculated that the normal form of the MGMT gene helps repair DNA damage including damage caused by chemotherapy study “We don't have to wait for to tumors and thus makes the drags less effective When the gene is methylated repair activity is blocked letting the anticancer drugs m Driver victim of road rage 1636 248 841 n - 001 001 002 012 009 NC -- 002 Putnam 1511 Glbi Growth Hi Yield TE Income Voyager Gr&lncome Van Kampen 013 1 2909 - 1373 1304 '2050 Pace ' -- 002 1962-00- 5 USA 016 878 857-00- 006 001 Growth - 003 003 009 ' The Bear River Health Department Is having a cancer screening clinic for women ages 50 to 64 from 8 am to noon Thursday at the health department Free pap smears pelvic eXams breast exams and grocery certificates will be given to women with low to medium annual household incomes To schedule an appointment call ext 100 752-37- 30 Cache Far South Company of Daughters of Utah Pioneers pm Thursday in the Hynun Civic Cento1 Eliza Mathews will be the contributing camp and will honor Donna Mae Crowshaw Company officers meet at 1:15 pm will meet at 2 V J Trapper Trails Council of the Boy Scouts of America is hosting a den chief conference Saturday Dec 2 Any Scout wishing to become a den chief is invited Scouts should tell their them at the November scoutmasters who should or Bob Holbrook at roundtables or call Dale Bright at pre-regist- er 258-29- 08 563-119- 1 Commodities POCATELLO Idaho (AP) — Idaho Farm Bureau Intermountain grain and livestock report for OGDEN — White wheat 256 (up 385 (steady) 14 percent' spring 330 (steady) 1 1 percent winter 301 (down 1) 362 (up 2) barley 410 (steady) springer heifers na baby calves 75- 140hd fat lambs na bulls 3600- - Livestock 4200 PORTLAND — White wheat 288 (up 1) barley 9550-960- 0 (up 50) 14 percent spring 416 (steady) 11 wood Livestock on Friday Utility and 1) barley LIVESTOCK AUCTION —Cotton- Grain POCATELLO — White wheat ' 23)5 (steady): barley 400 (steady) percent winter " 14 percent spring 334 (up 5) ordF downS) nary winter 291 (up J) CALDWELL 380-38- 1 (down 1 to — White wheat cwt heavy 7000-810- 0 -' 82QO:8700 feeder heifers light feeder heifers' stocker heifers' 9200-1030- 0 stock cows commercial cows 3100-380- 0 heavy feeder steers 7200-820- 0 light feeder steers 8800-990- 0 stocker steers 9600-1120- 0 light holstein feeder steers na heavy holstein feeder steers na holstein 600-750h- d stock cows with calves 700-8- 1 0pr Wearier pigs na feeder lambs na Remarks: light calves and cows steady heavy calves $1-- 4 lower active stock coy i market Nows of record BIRTHS Logan Regional Hospital KUNZ—r Leslie a girl Nov 6 ' DeVon Millville a LABRUM — Rhonda Lee Farnsworth i girl Nov 6 - Lachelle Newton and Eric Preston a LINDHARDT — girl ‘ : 6 Nov LUTZ — Chfcree Field and Derren Fish Haven a boy Nov 6 i yVHfmldlniimal BrtJgrritmli Duly Nrrsfiprr i USPS ' I' Utah Telephone1 i ’’ 0 41S) Toll 1 (800) : ' Mortgage " 7 'tr ' ''"'I 50e ' OneMundL'Carrieriluhi One Year Carrier (Utahi One Month Carrier i Idahni ' ' Single Cops Sunday SafaKfiption :':W50 $11400 $I00Q ))SI2000 One Year Carrier ( Idaho OneMuttth MaiL il7D0 ' ' ' One Yea MaiL S2W00 MSutKTUn Mat Ba PaJ hldwnca : ' hUti ntolKhdt apph4lt Uisi sales tu Suhscriheis not receiving deliseiy of their Herald Journal by 5:00 pm M- -f or 7 am Saturday 1 or mil free from Utah ft pleucphoK your camer-o- r The Herald Journal at Idaho behee 7 pmL6a weekdays I0D0 aim Saturday and 10:00 am Sunday for sour earner's name and pin me number please phone 712-21or toll free horn Utah ft Mato 7:30 am and 7 pm Monday through Friday Saturday from 1:00 am In ' 10:00 am Sunday fromlflllm to HM am Advertisers purchase space'and circulation only1 All property rights to any adseitisemeat produced' fur the advertiser by The Herald Journal using art work and or typography furnished or arranged for by The Herald Journal shall be the property ofThe Herald Journal No inch ad or any pul thereof may he reproduced or assigned without the consent oTThe Hcrald Journal Post Please send address changes tek The Herald Journal PO Bos 487 Logan UT 84J234M87 Moratay-FrkO-y ’ Otllca Hours: 7 JO uh to 100 SMurduyMOuicloNoM - 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