Show - -$ The Salt Lake Tribune Cell Researchers Win Nobel Prize heck cked with take THE ASSOCIATED STOCKHOLM Sweden — Two Americans won the Nobel Prize in medicine Monday for shedding light on how cells communicate to speed the spread of killer diseases I 4 law- - her they '1 ! i pep- - and PRESS like cholera and diabetes t throughout the body Alfred Gilman and Martin Rodbell will split the $930000 prize for determining how a certain group of proteins can help transmit and modulate signals in cells much like a biological switchboard Their discoveries products of two decades of work have been "paramount" in helping scientists understand diseases that affect tens of millions of people around the globe said Professor Bertil Fredholm of the Karolinska Institute's Nobel Assembly While their research carried out over two decades has not netted treatments yet the institute said it ultimately might at of sica fear bor- - )wer 'f ned k tom- - I I our 1 well bout suit 4 ?ws 1 rite : 1 aid u're I'm NATIONWORLD Castro Keeping Clamp on Dissent 4 ) ieiftt ni- - The medicine prize was the first of this year's six Nobel awards to be announced Since 1901 when the first Nobel medicine prize was awarded 72 of 157 winners have been from the United States reflecting an American dominance in basic research especially after World War 31t C Gilman 53 is head of the department of pharmacology at The University of Texas Southwestern Medical Center at Dallas "I'm awestruck I'm more excited than I've ever been" Gilman said after the prize was announced He predicted more knowledge about the communication process inside cells "will help considerably in designing better drugs and control malfunctions for treatment of specific diseases" Researcher's Utah Godfather Knew He Would Win iter By Lee Siegel THE SALT LAKE TRIBUNE a of Louis S Goodman the University of Utah's retired pharmacology chairman was thrilled Monday when he learned that his godson won the 1994 Nobel Prize in medicine "I'm so excited I couldn't be prouder" the 88- Goodman said from his Salt Lake City year-olhome "I'm so happy I lived long enough to see it It's as if I had won it I'm so proud " Alfred Goodman Gilman pharmacology chairman of the University of Texas Southwestern Medical Center in Dallas shared the prize with Martin Rodbell for research that shed light on how cells in the body communicate with each other In the 1930s and early '40s Gilman's father — the late Dr Alfred Gilman — was Goodman's colleague and close friend at Yale University's pharmacology department When the younger Gilman was born in 1941 Goodman became his godfather and the source of his middle name The same year Gilman's father and Goodman Jul d -me 1 Mom Defends Locking Sons in Dog Cages P - - THE ASSOCIATED 3t1 ri I r i i :k i - if CATED wrote the first edition of a textbook used in medical schools all over the world Goodman and Gilman's The Pharmacological Basis of Therapeutics known as G&G Years later the younger Gilman became an editor of the text and eventually took it over from Goodman and his father who died in the 1980s Goodman said Goodman moved to the University of Utah in 1944 serving as pharmacology chairman until 1971 In the preface to the text's eighth edition published in 1990 the younger Gilman praised his Utah godfather saying he was "particularly proud of my middle name acquired as a tribute to a friend and colleague There would have been no G&G without Louis Goodman and pharmacology would have been much diminished" Goodman said he called his godson in Texas soon after the Nobel Prize was announced "He was delighted" Goodman said "I knew he because of the brilliant work he'd would win it been doing and because he'd won every other prize POST HAVANA — President Fidel Castro is trying to rescue Cuba's faltering socialist system by easing it toward more open trade and political relations with d Western countries including the United States But at the same time he is tightening his political grip at home diplomats and Cuban analysts said With Cubans suffering the most severe economic privations since the demise three years ago of Cuba's Soviet Bloc patrons Castro wants to ensure that any economic opening he allows will not unleash a political explosion the observers said Cuban leaders have portrayed the Sept 9 pact with the United States that ended the exodus of rafters toward Florida as the beginning of a dialogue that could broaden ties But authorities here continue to harass Cubans who seek contact with US officials according to sources diplomats and human-right- s Since Aug 5 when disturbances in Havana spurred the rafters' exodus police have accosted and confiscated documents from at least 23 opposition activists going to or leaving the US Interests Section the sources said Cuban officials are shunning US diplomatic receptions Academics who maintain contacts with American universities had their passports confiscated in a pattern that remained unchanged after the immigration accord "To the degree that there is any improvement with the United States Castro wants to be sure Cuba is the controlling actor" observed a Western diplomat "They want to improve things government to government but not people to people" said a Cuban intellectual "They want to be sure the Communist Party is in control" Foreign Minister Roberto Robaina said the government will not allow any new leeway for dissident groups inside the country because they are "manipulated from outside" In he agreed black-mark- Rebelde Amh 4111 ' Now is a great time to start with Gloria Marshall! 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No charges have been filed against Fabian° 36 or her mother Virginia Steele who also lived with the children By Julia Preston THE WASHINGTON 's a Te's under pressure from the Spanish government to an unusual meeting in Madrid with three prominent Cuban exiles Another meeting is expected but Robaina said that initiative would not lead to dialogue with groups inside Cuba "Nothing could be further from the truth" he said Friday The government has not lifted the house arrest imposed on Elizardo Sanchez the Havana-baseleader of the rights group that one of the exiles Ramon Cernuda represents Sanchez was arrested sources several months ago on what human-right- s said was a politically inspired charge of using gasoline "The opening of our country does not depend on any call from the outside" Robaina said In an ongoing governmental crackdown on dissidents at least 29 have been detained since early August including three who were beaten in police custody the diplomatic sources said The rafters' departure did little to vent the tension in Cuban society Shortages have spread discontent among young people teachers health workers and city dwellers who had expressed content before the cutoff of Soviet Bloc subsidies with the spare but predictable living that socialism provided "I'm not a person who gets into politics But that man has got me under a lot of pressure" said Delia a grocery store cleaning woman referring to Castro Stacked on each side of the couch in Delia's cramped living room were cages for her chickens which provide the eggs she no longer can get at the store In the seaside town of Alamar residents said small disturbances had erupted several times when electrical blackouts which are common occurred during a popular nighttime Brazilian soap opera titled "Happiness" Frustrated people charged into the street broke bottles and threw rocks with no particular target Cuba's leaders have acknowledged the discontent "Today the military political and ideological problem of this country is to find food" said Gen Raul Castro Fidel's brother and defense minister in an interview in the Cuban newspaper Juventud He Tightens Political Grip While Trying to Rescue Socialist System A NOBEL Medicine 1994 Rodtiell however deplored what he called today's emphasis on specific goals at the expense of unfettered basic research "The world ain't the same" he said at a news conference in suburban Washington "Now everything is targeted bottom line how to make a buck" Rodbell 68 retired in May from the National Institute of Environmental Health Sciences in Research Triangle Park NC because his basic research budget kept shrinking and he saw there would not be enough money to complete the fiscal year He now holds the title scientist emeritus s 4101b Vt A5 Tuesday October 11 1994 PROGRAM OREM UNIVERSITY MALL OF $7 50 PER VISIT NUMBER OF VISITS DETERMINED BY SUGARHOUSE WEIGHT LOSS NEEDS OUICKTRIM LAYTON HILLS MALL ADDITIONAL NEW PATRONS ONLY PLEASE OFFER EXPIRES 1014i54 — Residential Mobile a Homes & Commercial 0 - c9 (iQ 'HOT WATER- 1 0 ‘" -- 4 KING en0 TRADE IN YOUR OLD WATER HEATER INSTALLATION 01 eD r1"--1- r"I' 'I Our Key Preference Plan gives you something to call home about SAME DAY alto - Install Quality Install Energy Efficient Natural Gas 0 N z:: DESIGN - 4 0 t y -- 4 Fvt: 4 di k71T4':C:' k 1 : 1 great investment you're going to want to brag a littleThat's why we're offering a free $W long distance calling card once you join everyone in your phone book Will discover what a nice ring our Key Preference Plan has to it AP " BANK ' CI) rate requires Ke l'reterence I1in NlembeNhip and is awoldbit hi!' personal accounts only Key l'reterence l'Ion requires a M AV cheiking count a iinid time onlv and on a h!I the MAN t hocking wow& payment deduction required tor limn discount Calling card niter available It combined balances wne tiN RV basis 4111 belots S1110110 N1111111111111 'i at tune during the stakment LNL le a SO 011 tee is charged to Obtain oiling ord Otter available at fit" Hank SIOMM Utah only Subtect to credit approval A It 40 N "4 x) MEr f?41a73 1 rt 4 ilt! 1 Zel (- LENDER Nivmber FDIC ti tIfieuriiii inktiV 1) Ll'pltItt or:: up to a 1e0 discount on loans a Gold MasterCard' Card with no annual fee and much more In fact the Key Preference Plan is such a lb join the Key Preference Plan simply ()pen a Plan NOW checking account and maintain a balance of $1a000 in any combinadon of deposit accounts So stop by the Key Bank nearest vouThat way N'ou and The Key Preference Plan is Key I3mk's premium financial program Along with one of the highest CD rates available membership includes NATURAL v SIL)41 cud You'll get a package of preferred financial services plus a $10 calling 161vIN —1 r 3A-117'- Glass Lined Water Heaters BY e 1 (D 4-- - 0414 a OW - - x 1 1 - - - - -- -- -- 1 |