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Show SYNVISC HYLAN G-F 29 UEF SUMMARY OF PRESCRIBING INFORNAT hecrey eacticr ees pcgmi GFoeafta an aoisPease ea caetn athwoacepy oFoffer procedures. Reactorsgenerally abate mennaten ae ‘Clinical benef rom treatment may stil cccur irartes actors roto ayohecical fal and Oat yy yer doctor to weigh the and ks of SsroyouCovet War Seer fo Te ay Wwnar Srivisc? Sracos and wa sere mitre ats rae po Infanti an B ge and sa water. The two fans ere manu face tom yangoran subarua coneto cheken coms, Hyaluronan a natural chemical found nthe body ands present i particulary aout in ont issues and in the fd a isthe The y= own hylan ac ke 2 brant fence piconet pen esos beretoy ‘yaturonn, and there may be =rbe aly efPeao nantans tess Drovers ayo Noioeyenateay furan ees Sys peny# sees econ re) eo With so many endangered species in the world, why don’t scientists try to clone them and thus solve the problem? —A.J. Gordon, Irvine, Cal Manyplans are under Cloning be way, but they're meeting with strong opposition. yged The animals are endangered becausetheir hab- to save itats are disappearing. Critics arguethatcloning wouldn't changethat. In9 stead, theysay. it would species? provide a quick and unwelcomefix: the ability to maintain a limited population of carbon-copyanimals that humanscreateat will to live in artificial environments,such as zoos. I believe their argumentis weak. Cloning was neverintended asa replacementfor habitat preservation. Rather,it is a tool oflast resort for animal-lovers who are concerned that efforts at saving the natural environmentsare failing and that the animals will be lost forever otherwise. Myown concerwithcloningis that. if it succeeds, well-meaning people(like you!) maythen believethat the problem has been solved. This would be a terrible outcome,lessening the urgencyto pressforthe onlyreal solution: a world where animals can runfreeinthe wild. Wave cancorentycooled ala wih a ao 112 who recewed eiter Syrnsc 6 used to relieve knee pan due to patients do not get adeasate simple painklers or nercse and physical therapy, The mast pain reel and greatest a SUOESS occured 10 12 afte: Syrvsc WOW CAN | GET have: Other aaverse events reported clude: rash, hives, ching, fever, rau Sea, Neadache, dizziness hits, muscle Crames.. Should endangered My momis a teacher. An assignmentin one of her textbooks asked to determine the word that does not belong in this list: sharp, hook, flat and earth. The answer was “sharp,” but she doesn’t know why. No one else knowseither. Do youP —Brad Berg, Watford City, ND. Theansweris on the next page.(Hint: Maybe the book wasa sciencetext.) to (sos ‘Do not inject Symvsc inthe knees of patients having knee joint ‘fect orn eases or fectonsWe area re yecbon WARNINGS * Do rot concomitanty use dsinfactants containing quatemary ammanium salts fr sn reparaton because hyaluronan can ‘recital their presence. * DarttS enaretry.he syovalees ‘nd capsule. Local and sysadverse evens, generally inthe eteecon tae conaed thong este aleHer fon o! * Intravascurar injections of Syrvisc may cause systemic adverse events PRECAUTIONS Te efecneess ol «ange reamen cyof et han Bree Injections oF Syrwsc has not been establ © 2002. Wyeth Prarmaceutcals, Prtadeionia. PA 19101 SYNVISC is develooed and manufactured by Genzyme Biosurgery, 2 <hision of Genzyme Corporation, and marketed and distributed Dy maceuticas Information about Synvsc F youwant fe rare askyu eoe ophamacst et ‘ead the professional label Tis Brief Summary for Dret-tSpec Pyscan hao. 60823 ReedFoousy13.2000 genzyme Wyeth’ 10329301 SYNVISC See ecxe is ee by most oe plans. Méany require tna doci provide SYNVISC. Hf your doctor does rot provide SYNVISC and F some insurance plans, an the coepeetigrecommended hat eu Neere, May not covererthe You ahyour aoc hearer ofee woe SYNVSC Procedures from policy to policy, so please check with ‘and/or your insurer.YOU questions about insurance coverage, please contact thes SYNVISC. eee Hot Line at ado960 2090, ‘This toll-free number Gite sromesl bowean 500 sian coven ean tine Monday through Frid FREE “Knee Pain Relief Kit" Please complete this postcard orcall 1-888-618-1682for a video featuring Nancy Lopez, Hall of FameProfessional Golfer and SYNVISC recipient, a booklet, and list of SYNVISC providers near you. MARIS MS. _ Appress is A cry = STATE ze PHONE EMAIL YEAR OF BIRTH 19 | wishto be includedin future mailings about SYNVISC or OA of the knee, Yes No All informationis confidential, We do not sell namesor information to others. Your e-mail address and any personal information you provide will be kept PRIVATE and CONFIDENTIAL Signature: SYINVISC is generally well rolerated: for everyone. The mat commonly reported se elects are temporarypin meling and/or hid accumsan theices nus soe vol ass gen in studhes used approve the proc i the US) fad accumution i are oFpa Cal your Gover Out tan ioc ach wreak ne erent with SY" SC.advise your doctor W you ae ae eo product from been reported rarely. Before you " birds, suchas feathers. eg or pouty, your lgSwale or fected The Feu of repeat use ave rox been erabtahed Wye . womsynvisccom Gore Wyeth 2002. Wyeth Pharmaceunicals Philadelphia PA 19101 103293.02 2002 SYINVISC regarered trademark of Genzyme Blosurgery. 3 dration of Genzyme Corporation developed and ranufactured by Genzyme Boturgery and marketed and dstnbted by Wyeth Pharmaceutical { PARADE ANSERCARD. HYLAN G-F 20 PRINTEDIN USA |