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Show PKAI2 Tilt DAILY Ht RAID, hemldrtirt ttmnu ClUTi I. TIMPANOOOS REQIOMAl HOIW-TA- Mv. 1: Boy to Kruty iVa and Donald Christoprw Archibald of Bountiful, Boy to Tricla Dawn and David Dougiat Dunitan of American fork. Girl to Haatnar and Michaal Joel Graham of Provo. Boy to Stacey Ann Olion and Derek Shane Nelson of American Fork. Boy to Robyn Cheryl and John Thomaa Williams of Oram. Nov. 2: Boy to Starr Rebecca and George C. David of Provo. Boy to Stephanie and Joseph Merrill Tennant of Alpine. Nov. S: Girl to Airica Elizabeth and Jose Jeffery Machuca of Sprmgville. Nov. 4: Boy to Deena Maria and Shann FinLmson of Lehl, Girl to Julie Ann and Scott Allen Iverson of Orem. Girl to Rebecca Jean and Fiedenck Michael Unwell of Provo. Boy to Ken Lynn and Taylor Brent Loesch of Provo, Boy to Alikha and Sienton Hearron Ross of Provo. Nov. : Boy to Tamra Mirae and Paul Jay Jenson of Provo, Nov. 7: Girl to Emily Ondina and David Edwin Baird of Spanish Fork, ' : UTAH VALLIV REGIONAL MEDICAL CENTER: Deo. 11: Girl to Laura Anne and Robert Brian Anderson of Provo, ' Boy to Alicia Marie and Michaal f homas Compton of Provo, Girl to Amy Lucille and Casey ; Oaniel Foots of Provo. ; Boy to Jan Kapiolanl and Timothy David Grotegut of Sprlngville, Girl to Holly Ann and Scott Robert Halvorsen of Orem. Girl to Jolayne and Christopher Norman Kline of Provo, Girl to Tami Rae and Anthony Mark " Miller of Provo, Girl to Kasha Dawn Orton of Greenville. Boy to Kathuna Maree Williams of Ephralm, Dee. 12: Boy to Kacey and Ryan Christer Tejler Englund of Springville, Girl to Katherine Camilla and David Stokes Hone of Provo, Boy to Tara Kaye and Gary Floyd Leikness of Provo, Girl to Joey and Jason Francis Payne of Springville, Boy to Elalna and Matthew Robert Paulsen of Provo. Boy to Marl Anne and David Squire Rollins of Orem, Girl to Nicole and Christopher Russell Thomas of Spanish Fork, Dee. 13: Girl to Star Dianne and Daniel Kenneth Balls of Provo, Boy to Sharon and Steven Clinton Branam of Spanish Fork. Boy to Maria Gayle and Matthew Arnold Call of Provo, Boy to JoLynn and Jose Luis Carter of Springville. Girl to Jill Marie and Michael Jordan Darrlngton of West Wendover, ' Girl to Kristyn Marie and Eleftherios Nlcholaui Efstratis of Pn, t ult, SukU. January 2, 2) EST A7, IfL'f! to disguise them from the immune system. We undertake Gene therapy is the fu-lattempting to find ways to curt, at the gene level, the moment come when we attempt the therapy with real live though ofttimes ' unhealthy - human. (cystic fibrosis, multiple type of cancer, Parkinson discaae, hemophilia, etc), The baaic aim is to identify the precise gene which in defective in these condition, isolate healthy version of the gene from other persons, load the new gene into some rt of "vector" or carrier syntem (usually a crippled virus), inject many copied of this vector into the recipient patient, and hope that enough of the good gene will get into the recipient' cell, and function therein, to ameliorate or eurithe diacaHC. For a variety of reasons, crippled virunes have seemed to be the most promising vector, Hut viruses have their own protein coat, and our bodie detect those and make antibodies againt them, So we try ( OUR FIRST attempt at that were in 191M) and were unsuccessful. The year 1994 . aw the firitt apparently A few smattering successes have come since, but much more extensive i the lit of failure. Numerous patients have died because the therapy just did not work well enough to save their lives. Hut now come the first death apparently caused by the treatment itself, and it Lresea&Ciieij'G. ter a bit until we have gleaned the common cold). , Such viruses have been lisecf quite extensively and only rarely has any untoward reac-- . V (ion been seen. The first ill in no had trial the patient effects. Jesse, the second, was injected with 38 trillion virus particles, and almost immedi- - j ' ately began to show medical stress. His' fever went to above 104; by the second day he was in a coma and his lungs filled with fluid. On the fourth day he died. ' Extensive autopsies have of course been done. The clinical trials were halted.' Investigations by multiple Hut no agencies are answers are yet available. Was Jesse just one of those unfortunate people who reacP negatively to a treatment that would be harmless for nearly everyone else? Or Is there something inherently defective in the treatment? What is sure is that the entire research effort will stut rccinM&coci'TY extend ve, laborious animal tests. Hut eventually the big huge hot of diseases that are cauwd by defects in our genes a4kM mam sftaoous fid eaps; (Stem C w sue-ce- Duane Jeffery ' all we can from this unfortu- nate happening. This delays the day of effective therapy: how many patients will die who may have been saved if the Gelsinger trials had worked? On the other hand, how many will be saved due to the increased safety features that will come as result of Jesse's death? ' ' IN THE meantime, other workers are experimenting with something like 200 other viruses as possible vectors. And Chromos, a company in Vancouver, B.C., reports that they have created the first transgenic animal, a mouse, which carries (and transmits to its offspring) a fully artifi- : helps the body get rid of the excess ammonia that builds up as a result of our regular metabolism of proteins, With drugs and a tightly regulated diet, Jesse got along pretty well, Hut he decided to participate as one of 18 involved a person who probapatients in a clinical trial at bly would have lived except forv j'enn State University which the procedure. Jesse CJelsinger, woyld use a crippled adenovirus (a family of ca. 40 virusa fairly healthy es originally Isolated from from Tucson had defective human adenoid tissue, and gene for ornithine transcar-bamylas- e associated with such things as an enzyme which on-goin- cial chromosome. Artificial chromosomes just may circumvent the viral vector problem, Duane Jeffery It aprofeunor of zoology at Drigham Young Unlvertity. Curious claim of occupation clashes with defendant's not guilty plea exited Interstate 91, arreting officer Michael Carrier said Tuesday, Hardy admitted to having two rocks of crack cocaine and turned it over to police, Carrier said, Later, on an application for a public defender, Hardy listed his occupation as "selling drugs," according to court records. In granting Hardy a public defender, Acting Judge David Gibson said selling drugs did- - HRATTL1CBORO, Vt. (AP) Norman Hardy Jr, pleaded innocent to drug charges. Hut when asked to list his occupation? Well, he sent a mixed message, "Selling drugs," ho told the. court. Hardy, 22, of Hruttleboro was arrested Saturday after police received a tip that alleged ho would bo returning to Vermont from Springfield, Mass,, with crack cocaine. Police spotted the car as it and ends . going to put up with this fool-- , ishness," said Charles Adamski, who was board presi- Sara, 18, who sports an eyebrow ring, and her sister Cadie, who had her nose pierced for her 15th birthday, aren't allowed in class unless they remove their piercings. voted Their school-boarlast month to amend the district's dress codo to ban body piercings, except in the ears, and the district reserves the right to evaluate "any emerging trend." "We wanted to let the student body know we weren't ODDS n't qualify as wage income, The judge ordered I lardy held on $5,000 cash bail. Piercings banned AL1QUIPPA, Pa. (Angara Newton wants to get an education but her jewelry is getting in the way, dent when the amendment was approved for the Hopewell Area School District, Hut Vic Walczak, the head of the local American Civil Liberties Union chapter, dis- - ' agrees, "Something more is going on here than kids' health and safety," ho said. Districts that . impose such a ban "want to control what these kids look like." J Complete pair packages from 59' to Provo, Boy to DeDe Kae and Robert Daniel Hathaway of Spanish Fork, Girl to Nicole and Kyla Lawrence Lefebvre of Provo, Boy to Hell B, and Randy Jay Links of Payson. Girl to Jenny Lynn and Alkw Dale Loftus of Spanish Fork, Boy to Tonya Lynn Faio of Provo, Girl to Maria Gabriela Amador of 'Hit i fJ Provo, Boy to Wendy and David John Schaerrer of Orem, Boy to Jessica Nicole Whitby of .1 ..V V ' - Orem. Dee. 14: Girl to Amberly and Clifton Taylor Brlmh&ll of Payson, Boy to Hollie Ann and Steven jli James Griffith of Orem, Boy to Carma Lynn and Kepi Vakasioula Helmuli of Provo, Boy to Dayna Michelle and Denmark Ray Jensen of West Jordan, Girl to Karina Paula and Arturo Leon of Qrom, Girl to Shares Alamo and Ttiyior Watson Snyder of Provo, Girl to Claudia and Corbott Kempton Stephens of Spanish Fork, Boy to Shannon Lyn and Jeremy Stephen Vincent of Provo. Dee. IS: Boy to Sandra and Galen Spencer Landon of Provo. Boy to Nancy Allison and Michael Lee Leach of Oram. Girl to Elizabeth Abigail and Lane Edward Livingston of Orem, Girl to Kathryn and Michael David Maddm of American Fork, Boy to Bethany and Benjamin Joseph Ritchie of Provo, Dee. 16: Girl to Karalyn Elizabeth and Ronald Blair Adams of Spanish Fork, Boy to Dana Lynne and Joshua Bradford Chappell of Springville, Girl to Cheryl LaRee and Damon : Dart Crockett of Springville, .. Boy to Shalynn Rae and Timothy ; I I I j ll ' a-- l; v If k i ' f 1; i fj y j 7 V!' i of Provo. Girl to Sandra and John Duane ; ', 1 j New Glass wear - It's horo, Come seo hundreds of Wolcome lo SuporTargot Optical, WFtoio llio glusswear Is high fashion for'your face, now, if It's fresh, if II? 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Ws match PEPH, IHC, VHC k IV - 1 Gene Cross of Mapletnn, Girl to Nikkole Mae Dierllrig of Payson, Boy to Lisa and Chad David Hays Hutchison of Orem, Boy to Tyrle Ann and Jeffery Leon ; Jones of Orem. Girl to Virginia May and Levi Joe ; Juggort of Springville. Girl to Jessica Jill and Brian Richard Lytle of Provo, ! Girl to Stephanie and James Reed 'Marziale Jr, of Spanish Fork, ; Girl to Mundl Lyn and Bret Jon Perrero of Springville, ; Boy to Veronica Ester and Larry Dean Peterson of Provo. J Boy to Krlsta Dawn and Jeremiah Mark Radandt of Provo. ' Girl to Katherine Lynne and Benjamin Robert Reng of Draper, Girl to Mary Lynn and Barton D. Schaerrer of Llndon, Dee. 17s Girl to Heather and Neal Kim Baker of Orem. Girl to Alicia Marie and Daniel Jason Butterfield of Provo. Girl to Brenda Raa and Kevin Scott Coleman of Marysvale, Girl to Patricia Lyn and Bryce Hiatt Eardley of Provo: Boy to April Louise and Michael Andrew Hanosek of Provo. " , Boy to Priscllla and Brent J. ' Harrison of Orem,' ' Girl to Jennifer and Jason Carl Kern of Orem. Girl to Marina Ausena and I Salomon Lira of Provo, ( Girl to Emily Joy and David Morrison Thomas of Provo; Boy to Ranee Puananl Yukian and Eric Thomas of Orem. Boy to Sherry Lynn and Jay Lynn Wall of Wallsburg. ' ' ! 1 and DMBA Imuroncs Programs, Aik for details. |